Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244903 | 1.00 | HPGD (0.41) | HPGDKMT2AGAAMEN1NPC1 | |
| SCHEMBL11265655 | 0.85 | KCNMA1 (0.48) | HPGDKMT2AGAAMEN1NPC1 | |
| SCHEMBL11265652 | 0.85 | KCNMA1 (0.48) | HPGDKMT2AGAAMEN1NPC1 | |
| SCHEMBL11246811 | 0.84 | CA12 (0.40) | KMT2AMAPTKDM4E | |
| SCHEMBL11246823 | 0.84 | CA12 (0.40) | KMT2AMAPTKDM4E | |
| SCHEMBL14257534 | 0.84 | KMT2A (0.47) | HPGDKMT2AGAAMEN1NPC1 | |
| SCHEMBL14267810 | 0.84 | KMT2A (0.39) | KMT2AMEN1POLB | |
| SCHEMBL14257580 | 0.84 | NPC1 (0.46) | HPGDKMT2AGAANPC1RAB9A | |
| SCHEMBL4777719 | 0.84 | RAB9A (0.43) | HPGDKMT2AMEN1NPC1ALOX15 | |
| SCHEMBL3644300 | 0.84 | KMT2A (0.47) | HPGDKMT2AGAAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321393-A | Method for preparing 2-cyanamidobenzimidazoles or 2-cyanamidobenzoxazoles | SMITHKLINE CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4285878-A | N-Phenyl-N'-cyano-O-phenylisoureas | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |