Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11265655 | 1.00 | KCNMA1 (0.48) | KCNMA1GAAMAPTHTTPOLB | |
| SCHEMBL11246823 | 0.86 | CA12 (0.40) | KCNMA1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL11246811 | 0.86 | CA12 (0.40) | KCNMA1MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL11244903 | 0.85 | HPGD (0.41) | GAAMAPTHTTPOLBKMT2A | |
| SCHEMBL11244909 | 0.85 | HPGD (0.41) | GAAMAPTHTTPOLBKMT2A | |
| SCHEMBL23576281 | 0.81 | KMT2A (0.43) | GAAMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4777722 | 0.81 | RAB9A (0.43) | POLBSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL4777719 | 0.81 | RAB9A (0.43) | POLBSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL14257564 | 0.81 | RAB9A (0.43) | POLBSMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL12708322 | 0.81 | KMT2A (0.43) | GAAMAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321393-A | Method for preparing 2-cyanamidobenzimidazoles or 2-cyanamidobenzoxazoles | SMITHKLINE CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4285878-A | N-Phenyl-N'-cyano-O-phenylisoureas | SMITHKLINE CORPORATION (US) | 1981-08-25 | — | — | US | disclosed |