⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931740 | 0.85 | — | — | |
| SCHEMBL930736 | 0.85 | — | — | |
| SCHEMBL930678 | 0.80 | — | — | |
| SCHEMBL1066665 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL7743557 | 0.77 | — | — | |
| SCHEMBL28314978 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL2241328 | 0.77 | — | — | |
| SCHEMBL6909484 | 0.76 | TSHR (0.39) | — | |
| SCHEMBL4199404 | 0.76 | TSHR (0.39) | — | |
| SCHEMBL2250864 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349388-A | Asphalt compositions modified with organo silane compounds | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
| US-4292371-A | Asphalt compositions modified with organo silane compounds | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |
| US-4273588-A | Asphalt compositions modified with organo silane compounds | OWENS-CORNING FIBERGLAS CORPORATION (US) | 1981-06-16 | — | — | US | disclosed |