Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11248019 | 0.92 | CYP1A2 (0.44) | P2RX7POLBLMNACYP1A2CYP2C9 | |
| SCHEMBL11251356 | 0.83 | CYP1A2 (0.42) | P2RX7LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11249532 | 0.83 | ALDH1A1 (0.46) | P2RX7CYP1A2CYP2C9CYP2C19CNR1 | |
| SCHEMBL11246732 | 0.74 | PTGDR2 (0.52) | POLBLMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL1195159 | 0.73 | CYP2C9 (0.62) | P2RX7POLBCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11247967 | 0.71 | CYP2C9 (0.56) | P2RX7POLBLMNACYP1A2CYP2C9 | |
| SCHEMBL11252577 | 0.71 | CYP1A2 (0.52) | P2RX7LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL23399622 | 0.70 | CYP2C9 (0.44) | POLBLMNACYP1A2CYP2C9CYP2C19 | |
| Trifezolac SCHEMBL11182574 | 0.69 | KDM4E (0.51) | LMNACYP1A2CYP2C9CYP2C19PTGDR2 | |
| SCHEMBL11730237 | 0.69 | LMNA (0.49) | POLBLMNAPTGDR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |