Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984007 | 0.87 | CA2 (0.58) | CA2MTNR1AGAAHSD17B10FFAR1 | |
| SCHEMBL29444746 | 0.87 | CA2 (0.58) | CA2MTNR1AGAAHSD17B10FFAR1 | |
| SCHEMBL29481813 | 0.87 | CA2 (0.58) | CA2MTNR1AGAAHSD17B10FFAR1 | |
| SCHEMBL6984001 | 0.87 | CA2 (0.58) | CA2MTNR1AGAAHSD17B10FFAR1 | |
| SCHEMBL11235851 | 0.84 | CA2 (0.56) | CA2MTNR1AGAAHSD17B10FFAR1 | |
| SCHEMBL8282396 | 0.82 | CA2 (0.59) | CA2GAAFFAR1RAB9ASMN1; SMN2 | |
| SCHEMBL11027482 | 0.81 | CA2 (0.58) | CA2GAAFFAR1HTTRAB9A | |
| SCHEMBL8288367 | 0.81 | CA2 (0.51) | CA2MTNR1AGAAHSD17B10RAB9A | |
| SCHEMBL1107090 | 0.81 | CA2 (0.51) | CA2MTNR1AGAAHSD17B10RAB9A | |
| SCHEMBL17272701 | 0.81 | CA2 (0.58) | CA2GAAFFAR1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329348-A | ANTIDEPRESSANTS AND PSYCHOSTIMULANTS | CIBA-GEIGY CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0004358-B1 | N-OXACYCLYLALKYL PIPERIDINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | CIBA-GEIGY AG (CH) | 1982-01-06 | — | — | EP | disclosed |
| EP-0004358-A1 | N-oxacyclylalkyl piperidines, process for their preparation, pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1979-10-03 | — | — | EP | disclosed |
| US-4129655-A | Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans | CIBA-GEIGY CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |
| US-4104396-A | NEUROLEPTIC, ANALGESIC | CIBA-GEIGY CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |
| US-4039676-A | NEUROLEPTIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |