Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11222928 | 0.94 | CA2 (0.49) | CA2GAAHSD17B10HTTTSHR | |
| SCHEMBL17272701 | 0.87 | CA2 (0.58) | CA2GAAFFAR1TSHRRAB9A | |
| SCHEMBL15870243 | 0.87 | CA2 (0.58) | CA2GAAFFAR1TSHRRAB9A | |
| SCHEMBL11245432 | 0.84 | CA2 (0.56) | CA2MTNR1AGAAHSD17B10FFAR1 | |
| SCHEMBL11228381 | 0.83 | MTNR1A (0.40) | CA2MTNR1AGAAHSD17B10HTT | |
| SCHEMBL8282396 | 0.82 | CA2 (0.59) | CA2GAAFFAR1RAB9ALMNA | |
| SCHEMBL11224196 | 0.81 | CA2 (0.56) | CA2MTNR1AFFAR1HTTTSHR | |
| SCHEMBL6984007 | 0.81 | CA2 (0.58) | CA2MTNR1AGAAHSD17B10FFAR1 | |
| SCHEMBL6984001 | 0.81 | CA2 (0.58) | CA2MTNR1AGAAHSD17B10FFAR1 | |
| SCHEMBL29481813 | 0.81 | CA2 (0.58) | CA2MTNR1AGAAHSD17B10FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353901-A | HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIAMIGRAINE, VASOSPASTIC DISORDERS, ASTHMA | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |