Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.66 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242107 | 0.80 | CYP19A1 (0.63) | CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL1507825 | 0.80 | CYP19A1 (1.00) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL7387804 | 0.80 | CYP19A1 (0.61) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL11287252 | 0.78 | CYP17A1 (0.74) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL1507790 | 0.77 | CYP19A1 (0.71) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL7855823 | 0.77 | CYP19A1 (0.62) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL9490860 | 0.77 | CYP19A1 (0.66) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL1507754 | 0.75 | CYP19A1 (0.88) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL1507796 | 0.75 | CYP19A1 (0.68) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL1507734 | 0.75 | CYP19A1 (0.88) | CYP19A1CYP17A1CYP11B1CYP11B2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351948-A | Imidazole hydrazone derivatives | G.D. SEARLE & CO. (US) | 1982-09-28 | — | — | US | disclosed |