Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.66 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5721926 | 0.83 | CYP17A1 (0.51) | CYP19A1CYP26A1KMT2ACYP17A1CYP11B1 | |
| SCHEMBL11242107 | 0.80 | CYP19A1 (0.63) | CYP19A1CYP26A1KMT2ACYP17A1CYP24A1 | |
| SCHEMBL7387804 | 0.80 | CYP19A1 (0.61) | CYP19A1CYP26A1KMT2ACYP17A1CYP11B1 | |
| SCHEMBL27618666 | 0.80 | CYP19A1 (0.76) | CYP19A1CYP26A1KMT2ACYP17A1CYP11B1 | |
| SCHEMBL19054896 | 0.78 | CYP19A1 (0.73) | CYP19A1CYP26A1KMT2ACYP17A1CYP11B1 | |
| SCHEMBL11287252 | 0.78 | CYP17A1 (0.74) | CYP19A1KMT2ACYP17A1CYP11B1CYP11B2 | |
| SCHEMBL11245762 | 0.77 | CYP19A1 (0.66) | CYP19A1CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL19999188 | 0.76 | CYP19A1 (0.69) | CYP19A1CYP26A1KMT2ACYP17A1CYP11B1 | |
| SCHEMBL11436593 | 0.75 | CYP26A1 (0.52) | CYP19A1CYP26A1KMT2ACYP17A1CYP11B1 | |
| SCHEMBL19999180 | 0.75 | CYP19A1 (0.88) | CYP19A1CYP26A1KMT2ACYP17A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236944-A | C1-4 alkyl(4-(2-(4-C1-4-alkylphenyl)-2(1H-imidazol-1-ylmethyl) -1,3-dioxolan-4-ylemthlthio)phenyl)carbamate | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-08-17 | — | — | US | disclosed |
| EP-0335446-A2 | Agents for treating neoplasms | JANSSEN PHARMACEUTICA N.V. (BE) | 1989-10-04 | — | — | EP | disclosed |