Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245810 | 1.00 | GAA (0.41) | GAAMAPTRAB9ANOS3NOS1 | |
| SCHEMBL11193502 | 0.79 | NOS3 (0.40) | GAAMAPTRAB9ANOS3NOS1 | |
| Hydrochloric Acid SCHEMBL11187059 | 0.78 | NOS3 (0.39) | GAAMAPTRAB9ANOS3NOS1 | |
| SCHEMBL16886019 | 0.77 | NISCH (0.38) | GAAMAPTRAB9ATDP1LMNA | |
| SCHEMBL7332315 | 0.77 | NISCH (0.38) | GAAMAPTRAB9ATDP1LMNA | |
| SCHEMBL7332320 | 0.77 | NISCH (0.38) | GAAMAPTRAB9ATDP1LMNA | |
| SCHEMBL11177066 | 0.77 | NOS3 (0.41) | GAAMAPTRAB9ANOS3NOS1 | |
| SCHEMBL18820266 | 0.76 | GAA (0.41) | GAAMAPTRAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL11191691 | 0.76 | NOS3 (0.38) | GAAMAPTRAB9ANOS3NOS1 | |
| SCHEMBL11751662 | 0.76 | NAAA (0.38) | GAAMAPTRAB9ANOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001663-B1 | NOVEL 2-ARYLAMINO-HEXAHYDROPYRIMIDINES AND -IMIDAZOLIDINES, SALTS AND COMPLEXES THEREOF, METHOD OF PREPARING THE NOVEL COMPOUNDS AND FUNGICIDAL COMPOSITIONS WHICH CONTAIN THE NOVEL COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1982-05-12 | — | — | EP | disclosed |