Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11234077 | 0.95 | TSHR (0.41) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11234578 | 0.86 | TSHR (0.39) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11249163 | 0.84 | TSHR (0.44) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11247712 | 0.83 | MAOB (0.37) | ALDH1A1CYP2C19CA12CA1CA2 | |
| SCHEMBL9291563 | 0.81 | RARB (0.46) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11252870 | 0.80 | TSHR (0.36) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11234671 | 0.80 | L3MBTL1 (0.38) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11243674 | 0.79 | MAOB (0.33) | L3MBTL1LMNA | |
| SCHEMBL11246261 | 0.78 | TSHR (0.43) | TSHRMEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL11250705 | 0.77 | MAOB (0.39) | KMT2AALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |