Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAT2A | P31153 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GSR | P00390 | 2/20 | 0.44 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865563 | 0.84 | GAA (0.41) | CYP1A2HTTMAT2AGAAKMT2A | |
| SCHEMBL11248751 | 0.73 | ALDH1A1 (0.43) | CYP1A2HTTGAAKMT2AKDM4E | |
| SCHEMBL11859778 | 0.72 | POLB (0.42) | GAAKMT2A | |
| SCHEMBL29223912 | 0.72 | CYP1A2 (0.61) | CYP1A2HTTGAAKMT2ABRD9 | |
| SCHEMBL11783990 | 0.70 | TSHR (0.57) | CYP1A2HTTGAAKMT2AGSR | |
| SCHEMBL11853874 | 0.70 | CDK4 (0.41) | KMT2ATLR8MAPK14XDH | |
| SCHEMBL11824631 | 0.70 | SMN1; SMN2 (0.47) | HTTMAT2AGAAKMT2ATLR8 | |
| SCHEMBL16324945 | 0.70 | CYP1A2 (0.57) | CYP1A2HTTGAAKMT2AGSR | |
| SCHEMBL11248098 | 0.70 | CYP1A2 (0.45) | CYP1A2HTTMAT2AGAAKMT2A | |
| SCHEMBL17537376 | 0.70 | CYP1A2 (0.58) | CYP1A2HTTGAAKMT2ABRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005911-B1 | ANALGESIC 6-ACYLAMINOTETRAHYDRO-1,3,5-TRIAZINE-2,4-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESS FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-17 | — | — | EP | disclosed |
| US-4254122-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF PROSTAGLANDIN SYNTHETASE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-03 | — | — | US | disclosed |
| EP-0005911-A1 | Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-12-12 | — | — | EP | disclosed |