Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392730 | 0.86 | SMN1; SMN2 (0.48) | POLBKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL11840254 | 0.86 | HCAR1 (0.47) | ALDH1A1POLBHCAR1KMT2AMEN1 | |
| SCHEMBL11824631 | 0.85 | SMN1; SMN2 (0.47) | POLBKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL11394388 | 0.84 | HCAR1 (0.45) | ALDH1A1POLBHCAR1KMT2AMEN1 | |
| SCHEMBL11859778 | 0.80 | POLB (0.42) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11386179 | 0.80 | CDK4 (0.46) | ALDH1A1HCAR1KMT2AMEN1KDM4E | |
| SCHEMBL11840285 | 0.77 | KDM4E (0.47) | ALDH1A1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL11865563 | 0.77 | GAA (0.41) | ALDH1A1POLBKMT2AMEN1KDM4E | |
| SCHEMBL11388886 | 0.75 | ALDH1A1 (0.48) | ALDH1A1HCAR1KMT2AMEN1KDM4E | |
| SCHEMBL10254162 | 0.75 | TLR7 (0.43) | ALDH1A1KDM4ESMN1; SMN2HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4303440-A | Use of isourea derivatives and triazine derivatives in combination with gibberellins as plant growth regulators | SANKYO COMPANY LIMITED (JP) | 1981-12-01 | — | — | US | claimed |
| EP-0005911-B1 | ANALGESIC 6-ACYLAMINOTETRAHYDRO-1,3,5-TRIAZINE-2,4-DIONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND PROCESS FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-02-17 | — | — | EP | disclosed |
| US-4254122-A | ANALGESICS, ANTIINFLAMMATORY AGENTS, ENZYME INHIBITORS OF PROSTAGLANDIN SYNTHETASE | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-03-03 | — | — | US | disclosed |
| EP-0005911-A1 | Analgesic 6-acylaminotetrahydro-1,3,5-triazine-2,4-dione derivatives, pharmaceutical compositions thereof, and process for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-12-12 | — | — | EP | disclosed |