Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11392730 | 0.82 | SMN1; SMN2 (0.48) | POLBLMNAL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11840285 | 0.81 | KDM4E (0.47) | LMNAUSP2L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11824631 | 0.81 | SMN1; SMN2 (0.47) | POLBLMNAL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11248751 | 0.80 | ALDH1A1 (0.43) | POLBLMNAXBP1HSD17B10SMN1; SMN2 | |
| SCHEMBL11865548 | 0.79 | SMN1; SMN2 (0.44) | LMNAHSD17B10SMN1; SMN2KMT2AMAPT | |
| SCHEMBL11840254 | 0.76 | HCAR1 (0.47) | POLBLMNAL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL11865563 | 0.76 | GAA (0.41) | POLBLMNAHSD17B10L3MBTL1SMN1; SMN2 | |
| SCHEMBL11853874 | 0.75 | CDK4 (0.41) | POLBLMNASMN1; SMN2KMT2AMAPT | |
| SCHEMBL9137022 | 0.75 | ALDH1A1 (0.37) | POLBLMNAHSD17B10L3MBTL1KMT2A | |
| SCHEMBL11394388 | 0.74 | HCAR1 (0.45) | POLBLMNAKMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3973947-A | 1,3,5-Triazinediones and their use as selective herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-10 | — | — | US | disclosed |
| US-3951971-A | SELECTIVE HERBICIDES | FUCHS JULIUS JAKOB | 1976-04-20 | — | — | US | disclosed |