Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL343916 | 0.97 | ACHE (0.47) | NOS3NOS1ACHETDP1CHRNA7 | |
| SCHEMBL427794 | 0.97 | ACHE (0.47) | NOS3NOS1ACHETDP1CHRNA7 | |
| SCHEMBL3073684 | 0.97 | ACHE (0.47) | NOS3NOS1ACHETDP1CHRNA7 | |
| Fluoride SCHEMBL27624071 | 0.94 | NOS3 (0.45) | NOS3NOS1ACHETDP1CHRNA7 | |
| SCHEMBL28483628 | 0.90 | PTPN5 (0.47) | NOS3NOS1ACHETDP1CHRNA7 | |
| SCHEMBL12807984 | 0.90 | PTPN5 (0.47) | NOS3NOS1ACHETDP1CHRNA7 | |
| SCHEMBL9331652 | 0.85 | NOS3 (0.54) | NOS3NOS1TDP1UGT2B7ALDH1A1 | |
| SCHEMBL9331061 | 0.85 | NOS3 (0.54) | NOS3NOS1TDP1UGT2B7ALDH1A1 | |
| SCHEMBL9331190 | 0.85 | NOS3 (0.54) | NOS3NOS1TDP1UGT2B7ALDH1A1 | |
| SCHEMBL40655 | 0.85 | NOS3 (0.54) | NOS3NOS1TDP1UGT2B7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346242-A | Method for preparing substituted meta-phenylalkoxynitrobenzenes | AMERICAN CYANAMID COMPANY (US) | 1982-08-24 | — | — | US | disclosed |