Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL427794 | 1.00 | ACHE (0.47) | ACHETDP1NOS3NOS1CHRNA7 | |
| SCHEMBL3073684 | 1.00 | ACHE (0.47) | ACHETDP1NOS3NOS1CHRNA7 | |
| Ethane SCHEMBL11246075 | 0.97 | NOS3 (0.45) | ACHETDP1NOS3NOS1CHRNA7 | |
| SCHEMBL12807984 | 0.92 | PTPN5 (0.47) | ACHETDP1NOS3NOS1CHRNA7 | |
| SCHEMBL28483628 | 0.92 | PTPN5 (0.47) | ACHETDP1NOS3NOS1CHRNA7 | |
| SCHEMBL40655 | 0.87 | NOS3 (0.54) | TDP1NOS3NOS1UGT2B7ALDH1A1 | |
| SCHEMBL9331061 | 0.87 | NOS3 (0.54) | TDP1NOS3NOS1UGT2B7ALDH1A1 | |
| SCHEMBL9331190 | 0.87 | NOS3 (0.54) | TDP1NOS3NOS1UGT2B7ALDH1A1 | |
| SCHEMBL9331652 | 0.87 | NOS3 (0.54) | TDP1NOS3NOS1UGT2B7ALDH1A1 | |
| SCHEMBL8738417 | 0.86 | HPGD (0.52) | TDP1NOS3NOS1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114405437-B | Photoelectrocatalysis device and application thereof | 太原师范学院 | 2023-10-27 | — | — | CN | claimed |
| CN-114405437-A | Photoelectrocatalysis device and application thereof | 太原师范学院 | 2022-04-29 | — | — | CN | claimed |
| EP-4709725-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Progentos Therapeutics, Inc. (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233642-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | PROGENTOS THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | WO | disclosed |
| CN-118652881-A | SOM-ZIF-8-PEG carrier immobilized enzyme and preparation method and application thereof | 湖南理工学院 | 2024-09-17 | — | — | CN | disclosed |
| CN-114405437-B | Photoelectrocatalysis device and application thereof | 太原师范学院 | 2023-10-27 | — | — | CN | disclosed |
| EP-4257593-A1 | CHIRAL MULTIDENTATE LIGAND AND USE THEREOF IN ASYMMETRIC HYDROGENATION | SHENZHEN CATALYS TECHNOLOGY CO., LTD. (CN) | 2023-10-11 | — | — | EP | disclosed |
| WO-2023077643-A1 | CHIRAL MULTIDENTATE LIGAND AND USE THEREOF IN ASYMMETRIC HYDROGENATION | 凯特立斯（深圳）科技有限公司 | 2023-05-11 | — | — | WO | disclosed |
| US-20230124576-A1 | CHIRAL MULTIDENTATE LIGAND, AND APPLICATION THEREOF IN ASYMMETRIC HYDROGENATION | SHENZHEN CATALYS TECHNOLOGY CO., LTD (CN) | 2023-04-20 | — | — | US | disclosed |
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CORTEVA AGRISCIENCE LLC (US) | 2022-07-14 | — | — | US | disclosed |
| CN-114405437-A | Photoelectrocatalysis device and application thereof | 太原师范学院 | 2022-04-29 | — | — | CN | disclosed |
| WO-2010141768-A2 | POLYCYCLIC ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS | AMIRA PHARMACEUTICALS, INC. (US) | 2010-12-09 | — | — | WO | disclosed |
| US-20090215778-A1 | Alpha-substituted Arylmethyl Piperazine Pyrazolo [1,5-alpha]Pyrimidine Amide Derivatives | PANACOS PHARMACEUTICALS, INC. (US) | 2009-08-27 | — | — | US | disclosed |
| US-20080227978-A1 | Converting a carbonyl group within a substrate to a chiral alcohol moiety by reacting the carbonyl containing substrate with an organoaluminium reagent in the presence of a Group 5-12 transition metal based catalyst which is complexed with a chiral ligand; excellent yields | THE UNIVERSITY OF NOTTINGHAM | 2008-09-18 | — | — | US | disclosed |
| EP-1134226-B1 | Process for producing an optically active ruthenium-phosphine complex and process for producing an optically active alcohol by using the complex | TAKASAGO PERFUMERY CO LTD (JP) | 2007-01-03 | — | — | EP | disclosed |
| US-20030171544-A1 | Alcohol dehydrogenase and use thereof | DEGUSSA AG (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6596887-B2 | Reacting a ruthenium-phosphine complex with a specific optically active chiral diamine to deactivate one of the enantiomers and with another diamine to activate the other enantiomers | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2003-07-22 | — | — | US | disclosed |
| EP-1241263-A1 | Alcohol dehydrogenase and uses therefor | Degussa AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| US-20010039354-A1 | Process for producing an optically active ruthenium-phosphine complex and process for producing an optically active alcohol by using the complex | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-11-08 | — | — | US | disclosed |
| EP-1134226-A2 | Process for producing an optically active ruthenium-phosphine complex and process for producing an optically active alcohol by using the complex | Takasago International Corporation (JP) | 2001-09-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215778-A1 | Alpha-substituted Arylmethyl Piperazine Pyrazolo [1,5-alpha]Pyrimidine Amide Derivatives | THPO, DPYD, TPMT | ACHE 4162/4885TDP1 1290/4885NOS3 2923/4885 |
| US-20220220068-A1 | FUNGICIDAL ARYL AMIDINES | CYP1A1, CYP1A2, CYP1B1 | ACHE 744/4885TDP1 1424/4885NOS3 358/4885 |
| US-20030171544-A1 | Alcohol dehydrogenase and use thereof | ADH5, ADH1A, ADH1C | ACHE 1922/4885TDP1 1183/4885NOS3 3436/4885 |
| US-20230124576-A1 | CHIRAL MULTIDENTATE LIGAND, AND APPLICATION THEREOF IN ASYMMETRIC HYDROGENATION | H1-4, CHRM1, CHRM2 | ACHE 478/4885TDP1 3338/4885NOS3 2920/4885 |
| US-20010039354-A1 | Process for producing an optically active ruthenium-phosphine complex and process for producing an optically active alcohol by using the complex | DRD4, PNMT, DRD1 | ACHE 386/4885TDP1 3583/4885NOS3 1960/4885 |
| US-20080227978-A1 | Converting a carbonyl group within a substrate to a chiral alcohol moiety by reacting the carbonyl containing substrate with an organoaluminium reagent in the presence of a Group 5-12 transition metal based catalyst which is complexed with a chiral ligand; excellent yields | ADH5, ADH1C, CYP2E1 | ACHE 1349/4885TDP1 4730/4885NOS3 1798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.