Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889271 | 0.90 | MAPT (0.77) | MAPTADRB1ADRB3ADRB2CYP1A2 | |
| SCHEMBL11238941 | 0.84 | ATM (0.56) | MAPTADRB1ADRB3ADRB2ATM | |
| SCHEMBL11244044 | 0.83 | MAPT (0.69) | MAPTADRB1ADRB3ADRB2ATM | |
| Hydrochloric Acid SCHEMBL11235226 | 0.83 | ADRB1 (0.56) | MAPTADRB1ADRB3ADRB2ATM | |
| SCHEMBL11234633 | 0.82 | MEN1 (0.55) | MAPTADRB1ADRB3ADRB2ATM | |
| Hydrochloric Acid SCHEMBL11230526 | 0.82 | MAPT (0.68) | MAPTADRB1ADRB3ADRB2ATM | |
| SCHEMBL11237809 | 0.81 | MEN1 (0.54) | MAPTADRB1ADRB3ADRB2ATM | |
| Hydrochloric Acid SCHEMBL11236936 | 0.81 | ADRB1 (0.56) | MAPTADRB1ADRB3ADRB2CYP1A2 | |
| SCHEMBL6432407 | 0.81 | ADRB1 (0.59) | MAPTADRB1ADRB3ADRB2ATM | |
| SCHEMBL6432412 | 0.81 | ADRB1 (0.59) | MAPTADRB1ADRB3ADRB2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |