Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246086 | 0.90 | MAPT (0.63) | MAPTADRB1ADRB3ADRB2MEN1 | |
| SCHEMBL9620020 | 0.82 | MAPT (0.69) | MAPTSMN1; SMN2HTTADRB1ADRB3 | |
| SCHEMBL11465129 | 0.82 | MAPT (0.68) | MAPTSMN1; SMN2HTTADRB1ADRB3 | |
| SCHEMBL6480038 | 0.81 | MAPT (0.63) | MAPTSMN1; SMN2HTTADRB1ADRB3 | |
| SCHEMBL11814077 | 0.81 | MAPT (0.67) | MAPTSMN1; SMN2HTTADRB1ADRB3 | |
| SCHEMBL11571275 | 0.81 | MAPT (0.67) | MAPTSMN1; SMN2HTTADRB1ADRB3 | |
| SCHEMBL11448213 | 0.81 | MAPT (0.93) | MAPTSMN1; SMN2HTTADRB1ADRB3 | |
| SCHEMBL9661011 | 0.80 | MAPT (0.78) | MAPTSMN1; SMN2HTTADRB1ADRB3 | |
| SCHEMBL11246090 | 0.79 | MAPT (0.50) | MAPTSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL6630532 | 0.77 | MAPT (0.64) | MAPTSMN1; SMN2HTTADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582897-A | 2-AZO-4-SULFO-4-METHYLDIPHENYL SULFONE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0042357-B1 | AZO DYES, THEIR PREPARATION AND USE | CIBA-GEIGY AG (CH) | 1984-06-06 | — | — | EP | disclosed |