Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11269174 | 0.79 | TDP1 (0.45) | CCNE1CDK2CDK5CHRNA7 | |
| SCHEMBL11252606 | 0.78 | TDP1 (0.44) | CCNE1CDK2CDK5CHRNA7 | |
| SCHEMBL11267468 | 0.77 | ANPEP (0.38) | DGAT2KLKB1CYP3A4ANPEP | |
| SCHEMBL11267832 | 0.77 | TDP1 (0.45) | CCNE1CDK2CDK5CHRNA7 | |
| SCHEMBL11259018 | 0.76 | ALDH1A1 (0.39) | KLKB1ANPEP | |
| SCHEMBL11261376 | 0.76 | KDM4E (0.41) | CDK5NPC1RAB9ACHRNA7 | |
| SCHEMBL11260207 | 0.75 | TDP1 (0.35) | CDK5CHRNA7 | |
| SCHEMBL11266460 | 0.75 | CDK5 (0.38) | CCNE1CDK2CDK5CHRNA7 | |
| SCHEMBL11263036 | 0.74 | ALDH1A1 (0.40) | DGAT2KLKB1ANPEP | |
| SCHEMBL11260439 | 0.74 | TDP1 (0.47) | CCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |