Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.64 |
| ▸ | FBP1 | P09467 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ABL2 | P42684 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246287 | 1.00 | PTGS2 (0.64) | PTGS2FBP1ALDH1A1MAPTLMNA | |
| SCHEMBL9717619 | 0.86 | FBP1 (0.57) | PTGS2FBP1ALDH1A1MAPTLMNA | |
| SCHEMBL9717499 | 0.86 | FBP1 (0.57) | PTGS2FBP1ALDH1A1MAPTLMNA | |
| SCHEMBL9717504 | 0.86 | FBP1 (0.57) | PTGS2FBP1ALDH1A1MAPTLMNA | |
| SCHEMBL11259689 | 0.84 | CYSLTR2 (0.49) | PTGS2FBP1ALDH1A1MAPTLMNA | |
| SCHEMBL11259683 | 0.84 | CYSLTR2 (0.49) | PTGS2FBP1ALDH1A1MAPTLMNA | |
| SCHEMBL17559100 | 0.81 | FBP1 (0.55) | PTGS2FBP1ALDH1A1MAPTLMNA | |
| SCHEMBL17559101 | 0.81 | FBP1 (0.55) | PTGS2FBP1ALDH1A1MAPTLMNA | |
| SCHEMBL19397777 | 0.81 | FBP1 (0.55) | PTGS2FBP1ALDH1A1MAPTLMNA | |
| SCHEMBL8736030 | 0.80 | FBP1 (0.53) | PTGS2FBP1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023385-B1 | ETHANAMINE DERIVATIVES, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1982-12-15 | — | — | EP | disclosed |
| US-4338333-A | ANTIOBESITY, HYPOGLYCEMIC | BEECHAM GROUP LIMITED (GB) | 1982-07-06 | — | — | US | disclosed |
| EP-0023385-A1 | Ethanamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-02-04 | — | — | EP | disclosed |