Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 10/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633400 | 0.78 | MEN1 (0.77) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL6898556 | 0.76 | TDP1 (0.48) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL23786202 | 0.76 | KCNH3 (0.67) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL30568835 | 0.76 | KCNH3 (1.00) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL11257385 | 0.74 | MEN1 (0.55) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL18123046 | 0.74 | MEN1 (0.71) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL3294680 | 0.73 | KCNH3 (0.73) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL11936604 | 0.72 | MAPT (0.63) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL14869417 | 0.72 | GAA (0.81) | KCNH3MEN1MAPTKMT2AGAA | |
| SCHEMBL12634410 | 0.72 | GAA (0.81) | KCNH3MEN1MAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339577-A | CROSSLINKING INHIBITORS FOR RUBBERS | MONSANTO COMPANY (US) | 1982-07-13 | — | — | US | disclosed |
| US-4301260-A | Vulcanizable rubber compositions scorch inhibited by 2-(thioamino)-4,6-diamino-1,3,5-triazines | MONSANTO COMPANY (US) | 1981-11-17 | — | — | US | disclosed |