Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18460958 | 0.78 | TDP1 (0.41) | TDP1TSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL23381557 | 0.76 | MEN1 (0.41) | ALDH1A1RECQLNPC1RAB9AMAPK1 | |
| SCHEMBL11246375 | 0.76 | KCNH3 (0.61) | ALDH1A1LMNAGAAMAPK1SMN1; SMN2 | |
| SCHEMBL5182790 | 0.75 | ALDH1A1 (0.39) | TDP1TSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL18757692 | 0.74 | MEN1 (0.47) | TDP1ALDH1A1CYP3A4LMNARECQL | |
| SCHEMBL8525109 | 0.74 | TDP1 (0.39) | TDP1TSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL24093071 | 0.72 | RAPGEF4 (0.46) | ALDH1A1ALOX15NPC1RAB9AGAA | |
| SCHEMBL310486 | 0.70 | — | — | |
| SCHEMBL2552416 | 0.69 | ALDH1A1 (0.50) | TDP1TSHRHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL4557133 | 0.69 | ALDH1A1 (0.50) | TDP1TSHRHSD17B10ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077709-A1 | Neuronal death inhibitors | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
| US-4975362-A | Silver halide emulsion and a cyanine dye for use with diode lasers | EASTMAN KODAK COMPANY (US) | 1990-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077709-A1 | Neuronal death inhibitors | CASP3, CASP1, AIFM1 | TDP1 617/4885TSHR 4726/4885HSD17B10 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.