Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.55 |
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | PDE5A | O76074 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251441 | 0.94 | GBA1 (0.61) | GBA1APPPDE5AMAPTHTT | |
| SCHEMBL11260802 | 0.92 | GBA1 (0.54) | GBA1APPPDE5AACP1POLB | |
| SCHEMBL11245274 | 0.86 | APP (0.49) | GBA1APPPDE5AMAPTHTT | |
| SCHEMBL11245980 | 0.83 | EGFR (0.57) | GBA1APPMAPTHTTPOLB | |
| SCHEMBL11254611 | 0.82 | APP (0.50) | GBA1APPPDE5AACP1TLR7 | |
| SCHEMBL17799808 | 0.78 | SLC6A3 (0.61) | GBA1APPPDE5AMAPTHTT | |
| SCHEMBL17799832 | 0.77 | APP (0.58) | APPPDE5AMAPTHTTACP1 | |
| SCHEMBL11255510 | 0.76 | GBA1 (0.55) | GBA1APPPDE5AMAPTHTT | |
| SCHEMBL29161537 | 0.75 | APP (0.69) | APPPDE5AMAPTHTTACP1 | |
| SCHEMBL11254689 | 0.75 | MEN1 (0.59) | GBA1APPPDE5AMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |