Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.54 |
| ▸ | APP | P05067 | 7/20 | 0.50 |
| ▸ | PDE5A | O76074 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11251441 | 0.93 | GBA1 (0.61) | GBA1APPPDE5ASLC6A3ACP1 | |
| SCHEMBL11246670 | 0.92 | GBA1 (0.55) | GBA1APPPDE5ASLC6A3ACP1 | |
| SCHEMBL11254611 | 0.83 | APP (0.50) | GBA1APPPDE5ASLC6A3KDM4E | |
| SCHEMBL11258725 | 0.81 | RAB9A (0.54) | GBA1APPPOLB | |
| SCHEMBL11251275 | 0.78 | GBA1 (0.63) | GBA1APPPDE5AKDM4EALDH1A1 | |
| SCHEMBL11240404 | 0.78 | APP (0.52) | GBA1APPPDE5ASLC6A3KDM4E | |
| SCHEMBL11245274 | 0.78 | APP (0.49) | GBA1APPPDE5ASLC6A3ACP1 | |
| SCHEMBL17799808 | 0.77 | SLC6A3 (0.61) | GBA1APPPDE5ASLC6A3KDM4E | |
| SCHEMBL11246446 | 0.76 | GBA1 (0.54) | GBA1APPPDE5AKDM4EALDH1A1 | |
| SCHEMBL3113251 | 0.76 | APP (0.81) | GBA1APPPDE5AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |