Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.57 |
| ▸ | PDE5A | O76074 | 1/20 | 0.57 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240404 | 0.92 | APP (0.52) | APPPDE5AKCNA5GBA1TLR7 | |
| SCHEMBL11259177 | 0.89 | APP (0.49) | APPPDE5AKCNA5MAPTCYP1A2 | |
| SCHEMBL11250987 | 0.84 | APP (0.52) | APPPDE5AKCNA5TLR7MAPT | |
| SCHEMBL11245793 | 0.82 | EGFR (0.54) | APPMAPTHTTCYP1A2MAPK1 | |
| SCHEMBL17799955 | 0.82 | SLC6A3 (0.59) | APPPDE5AKCNA5TLR7MAPT | |
| SCHEMBL11240704 | 0.79 | APP (0.49) | APPPDE5AKCNA5GBA1TLR7 | |
| SCHEMBL11242446 | 0.78 | EGFR (0.57) | APPMAPTHTTCYP1A2MAPK1 | |
| SCHEMBL29161537 | 0.77 | APP (0.69) | APPPDE5ATLR7MAPTHTT | |
| SCHEMBL17799841 | 0.76 | APP (0.58) | APPPDE5AKCNA5MAPTHTT | |
| SCHEMBL11250201 | 0.76 | APP (0.63) | APPPDE5AGBA1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |