Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246699 | 0.92 | APP (0.57) | APPPDE5AALDH1A1KCNA5GBA1 | |
| SCHEMBL11259177 | 0.87 | APP (0.49) | APPPDE5AKDM4EALDH1A1KCNA5 | |
| SCHEMBL11250104 | 0.82 | EGFR (0.52) | APPMEN1LMNAMAPTKMT2A | |
| SCHEMBL11250987 | 0.82 | APP (0.52) | APPPDE5AKDM4EALDH1A1KCNA5 | |
| SCHEMBL11251275 | 0.80 | GBA1 (0.63) | APPPDE5AKDM4EALDH1A1GBA1 | |
| SCHEMBL11260802 | 0.78 | GBA1 (0.54) | APPPDE5AKDM4EALDH1A1GBA1 | |
| SCHEMBL17799955 | 0.78 | SLC6A3 (0.59) | APPPDE5AKDM4EALDH1A1KCNA5 | |
| SCHEMBL3113251 | 0.78 | APP (0.81) | APPPDE5AKDM4EALDH1A1GBA1 | |
| SCHEMBL11242446 | 0.77 | EGFR (0.57) | APPKDM4EALDH1A1MEN1LMNA | |
| SCHEMBL11245793 | 0.75 | EGFR (0.54) | APPKDM4EMEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |