Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246699 | 0.84 | APP (0.57) | APPPDE5AKCNA5CYP1A2CYP3A4 | |
| SCHEMBL11246726 | 0.82 | LDHA (0.50) | APPKCNA5CYP1A2HSD17B10KDM4E | |
| SCHEMBL11240404 | 0.82 | APP (0.52) | APPPDE5AKCNA5KDM4ETLR7 | |
| SCHEMBL11251043 | 0.80 | APP (0.56) | APPPDE5ASLC2A1CYP1A2CYP3A4 | |
| SCHEMBL11259177 | 0.80 | APP (0.49) | APPPDE5AKCNA5CYP1A2CYP3A4 | |
| SCHEMBL11254611 | 0.78 | APP (0.50) | APPPDE5AKCNA5SLC2A1CYP1A2 | |
| SCHEMBL17799955 | 0.78 | SLC6A3 (0.59) | APPPDE5AKCNA5KDM4ETLR7 | |
| SCHEMBL9776789 | 0.75 | APP (0.67) | APPPDE5ASLC2A1CYP1A2CYP3A4 | |
| SCHEMBL11240704 | 0.75 | APP (0.49) | APPPDE5AKCNA5SLC2A1CYP1A2 | |
| SCHEMBL11251106 | 0.74 | LDHA (0.49) | APPKCNA5CYP1A2HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |