Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.65 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 6/20 | 0.57 |
| ▸ | DRD1 | P21728 | 6/20 | 0.57 |
| ▸ | DRD4 | P21917 | 6/20 | 0.57 |
| ▸ | DRD5 | P21918 | 6/20 | 0.57 |
| ▸ | DRD3 | P35462 | 6/20 | 0.57 |
| ▸ | DRD2 | P14416 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11178955 | 0.97 | OPRM1 (0.70) | OPRD1OPRK1OPRM1HTR1ADRD1 | |
| SCHEMBL11178963 | 0.97 | OPRM1 (0.70) | OPRD1OPRK1OPRM1HTR1ADRD1 | |
| SCHEMBL11194604 | 0.96 | OPRM1 (0.69) | OPRD1OPRK1OPRM1HTR1ADRD1 | |
| SCHEMBL11194601 | 0.96 | OPRM1 (0.69) | OPRD1OPRK1OPRM1HTR1ADRD1 | |
| SCHEMBL11244026 | 0.92 | OPRD1 (0.69) | OPRD1OPRK1OPRM1DRD4DRD3 | |
| Bromide SCHEMBL11247569 | 0.91 | OPRD1 (0.67) | OPRD1OPRK1OPRM1DRD4DRD3 | |
| SCHEMBL11258195 | 0.86 | SLC6A4 (0.61) | OPRD1OPRK1OPRM1DRD2 | |
| Bromide SCHEMBL11248188 | 0.85 | SLC6A2 (0.50) | OPRD1OPRK1OPRM1 | |
| Bromide SCHEMBL11265180 | 0.85 | SLC6A4 (0.60) | OPRD1OPRK1OPRM1DRD2 | |
| Bromide SCHEMBL11247155 | 0.84 | SLC6A4 (0.59) | OPRD1OPRK1OPRM1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337341-A | 4a-Aryl-octahydro-1H-2-pyrindines | ELI LILLY AND COMPANY (US) | 1982-06-29 | — | — | US | disclosed |