Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252262 | 0.88 | PTGES (0.38) | ABCC8KCNJ11AMY1APTGES | |
| SCHEMBL11256340 | 0.88 | AMY1A (0.40) | ABCC8KCNJ11AMY1APIK3R1PIK3CA | |
| SCHEMBL11241077 | 0.86 | MPL (0.44) | ABCC8KCNJ11 | |
| SCHEMBL11260493 | 0.82 | MPL (0.36) | AMY1A | |
| SCHEMBL11261336 | 0.82 | MPL (0.36) | AMY1A | |
| SCHEMBL11260918 | 0.82 | AKR1C3 (0.33) | AMY1ADHODHPDE3BPDE3A | |
| SCHEMBL11262400 | 0.81 | CYP1A2 (0.40) | AMY1APTGES | |
| SCHEMBL11248679 | 0.79 | SCD (0.40) | — | |
| SCHEMBL11259416 | 0.79 | HDAC6 (0.34) | DHODH | |
| SCHEMBL11257902 | 0.79 | DHODH (0.32) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |