Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241077 | 0.90 | MPL (0.44) | MPLCYP11B1CYP11B2NPBWR1ALOX5AP | |
| SCHEMBL11249122 | 0.87 | NPBWR1 (0.31) | NPBWR1 | |
| SCHEMBL11258445 | 0.86 | ABCC8 (0.36) | NPBWR1 | |
| SCHEMBL11260493 | 0.86 | MPL (0.36) | MPLCYP11B2NPBWR1AMY1AALOX5AP | |
| SCHEMBL11247229 | 0.82 | ABCC8 (0.43) | AMY1A | |
| SCHEMBL11252262 | 0.82 | PTGES (0.38) | MPLAMY1AALOX5APFEN1 | |
| SCHEMBL11258492 | 0.81 | — | — | |
| SCHEMBL11248485 | 0.78 | TRPV1 (0.40) | NPBWR1 | |
| SCHEMBL11260918 | 0.78 | AKR1C3 (0.33) | AMY1A | |
| SCHEMBL11252082 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |