Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 11/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287124 | 0.95 | MAOB (0.43) | KMT2AMEN1KDM4ECRHBPCRHR2 | |
| SCHEMBL11281619 | 0.88 | MAOB (0.42) | KMT2AMEN1KDM4ECRHBPCRHR2 | |
| SCHEMBL11249099 | 0.87 | KDM4E (0.40) | KMT2AMEN1KDM4ECRHBPCRHR2 | |
| SCHEMBL11360922 | 0.82 | MAOB (0.43) | KMT2AMEN1KDM4EMAOBMAPT | |
| SCHEMBL11247457 | 0.77 | MAOB (0.39) | KMT2AMAOBTACR3ADORA2B | |
| SCHEMBL10961841 | 0.75 | KMT2A (0.48) | KMT2AMEN1KDM4ECRHBPCRHR2 | |
| SCHEMBL10961044 | 0.71 | KMT2A (0.47) | KMT2AMEN1KDM4ECRHBPCRHR2 | |
| SCHEMBL11123628 | 0.71 | PTGS1 (0.56) | KMT2AMEN1KDM4EMAPTLMNA | |
| SCHEMBL10963521 | 0.69 | KMT2A (0.53) | KMT2AMEN1KDM4ECRHBPCRHR2 | |
| SCHEMBL8311797 | 0.68 | MAOB (0.49) | MAOBACHEADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054578-A1 | N-(substituted chromone-3-carbonyl)-phenylglycine derivatives | Eisai Co., Ltd. (JP) | 1982-06-30 | — | — | EP | disclosed |