Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 7/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 10/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281619 | 0.92 | MAOB (0.42) | KDM4EKMT2AMAPTMEN1LMNA | |
| Phenylglycine SCHEMBL11247409 | 0.87 | KMT2A (0.40) | KDM4EKMT2AMAPTMEN1LMNA | |
| SCHEMBL11287124 | 0.85 | MAOB (0.43) | KDM4EKMT2AMAPTMEN1LMNA | |
| SCHEMBL11247457 | 0.81 | MAOB (0.39) | KMT2AMAOBALDH2MAOA | |
| SCHEMBL8311797 | 0.74 | MAOB (0.49) | MAOBMAOA | |
| SCHEMBL11360922 | 0.73 | MAOB (0.43) | KDM4EKMT2AMAPTMEN1MAOB | |
| SCHEMBL11123151 | 0.71 | PTGS1 (0.50) | KMT2AMAPTMEN1LMNA | |
| SCHEMBL10961841 | 0.71 | KMT2A (0.48) | KDM4EKMT2AMAPTMEN1LMNA | |
| SCHEMBL11153948 | 0.70 | NR1I2 (0.41) | KDM4EKMT2AMAPTMEN1MAOB | |
| SCHEMBL8122069 | 0.70 | MAOB (0.48) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054578-A1 | N-(substituted chromone-3-carbonyl)-phenylglycine derivatives | Eisai Co., Ltd. (JP) | 1982-06-30 | — | — | EP | disclosed |