Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 18/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | YARS1 | P54577 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8122057 | 0.90 | MAOB (0.48) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL8122069 | 0.90 | MAOB (0.48) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL8621258 | 0.83 | MAOB (0.48) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL11281619 | 0.81 | MAOB (0.42) | MAOBMAOAADORA2B | |
| SCHEMBL11247457 | 0.79 | MAOB (0.39) | MAOBMAOAADORA2B | |
| SCHEMBL9329500 | 0.76 | MAOB (0.46) | MAOBALOX15ALOX12MAOAADORA2B | |
| SCHEMBL11360922 | 0.76 | MAOB (0.43) | MAOBMAOAADORA2BACHE | |
| SCHEMBL11033235 | 0.74 | MAPT (0.40) | MAOB | |
| SCHEMBL11249099 | 0.74 | KDM4E (0.40) | MAOBMAOA | |
| SCHEMBL10682794 | 0.74 | MAOB (0.35) | MAOBALOX15ALOX12MAOAADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0093376-B2 | 1-Sulfo-2-azetidinone derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0093376-B1 | 1-SULFO-2-AZETIDINONE DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1990-03-21 | — | — | EP | disclosed |
| US-4782147-A | ANTIBIOTIC | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0093376-A2 | 1-Sulfo-2-azetidinone derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-11-09 | — | — | EP | disclosed |