Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 15/20 | 0.39 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | TACR3 | P29371 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281619 | 0.88 | MAOB (0.42) | MAOBMAOAADORA2BTACR3KMT2A | |
| SCHEMBL11249099 | 0.81 | KDM4E (0.40) | MAOBMAOAKMT2AALDH2 | |
| SCHEMBL11287124 | 0.81 | MAOB (0.43) | MAOBADORA2BTACR3KMT2A | |
| SCHEMBL8311797 | 0.79 | MAOB (0.49) | MAOBMAOAADORA2B | |
| SCHEMBL10964606 | 0.79 | MAOB (0.42) | MAOBMAOAKMT2A | |
| SCHEMBL10962062 | 0.77 | KMT2A (0.34) | MAOBMAOAKMT2A | |
| Phenylglycine SCHEMBL11247409 | 0.77 | KMT2A (0.40) | MAOBADORA2BTACR3KMT2A | |
| SCHEMBL11360922 | 0.75 | MAOB (0.43) | MAOBMAOAADORA2BTACR3KMT2A | |
| SCHEMBL10964135 | 0.71 | PTPN1 (0.47) | MAOBMAOAKMT2A | |
| SCHEMBL8122069 | 0.70 | MAOB (0.48) | MAOBMAOAADORA2BTACR3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0054578-A1 | N-(substituted chromone-3-carbonyl)-phenylglycine derivatives | Eisai Co., Ltd. (JP) | 1982-06-30 | — | — | EP | disclosed |
| US-4331606-A | BACTERICIDES, CEPHALOSPORIN INTERMEDIATES | EISAI CO., LTD. (JP) | 1982-05-25 | — | — | US | disclosed |