Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310726 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9110496 | 0.82 | ALDH1A1 (0.54) | SMN1; SMN2NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2866892 | 0.76 | ALDH1A1 (0.56) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL4782825 | 0.74 | ALDH1A1 (0.55) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL2499727 | 0.72 | ALDH1A1 (0.52) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL29833357 | 0.71 | ALDH1A1 (0.51) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL13975631 | 0.71 | KMT2A (0.53) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL27796240 | 0.69 | ALDH1A1 (0.52) | SMN1; SMN2NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL12069840 | 0.69 | ALDH1A1 (0.54) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL104954 | 0.69 | MAOA (0.53) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067641-A2 | Amino acids | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | claimed |
| EP-0067641-A2 | Amino acids | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |