Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 2/20 | 0.60 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.58 |
| ▸ | PI4KA | P42356 | 3/20 | 0.58 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.58 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.58 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | NSD3 | Q9BZ95 | 4/20 | 0.51 |
| ▸ | NSD2 | O96028 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25306268 | 0.88 | ENPP1 (0.61) | ENPP1NT5EADORA2AADORA1PI4KA | |
| SCHEMBL10566016 | 0.87 | ENPP1 (0.59) | ENPP1NT5EADORA2AADORA1PI4KA | |
| SCHEMBL20096689 | 0.87 | ADORA2A (0.66) | ENPP1NT5EADORA2AADORA1PI4KA | |
| SCHEMBL2293269 | 0.87 | ADORA2A (0.66) | ENPP1NT5EADORA2AADORA1PI4KA | |
| SCHEMBL29385353 | 0.84 | ADORA2A (0.57) | ENPP1NT5EADORA2AADORA1PI4KA | |
| SCHEMBL18786971 | 0.84 | ADORA2A (0.57) | ENPP1NT5EADORA2AADORA1PI4KA | |
| SCHEMBL5065704 | 0.83 | ADORA2A (0.59) | ENPP1NT5EADORA2AADORA1PI4KA | |
| SCHEMBL9885880 | 0.83 | ADORA2A (0.69) | ENPP1NT5EADORA2AADORA1PI4KA | |
| SCHEMBL14425475 | 0.82 | ENPP1 (0.61) | ENPP1NT5EADORA2AADORA1PI4KA | |
| SCHEMBL20096700 | 0.82 | ADORA2A (0.64) | ENPP1NT5EADORA2AADORA1PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4360522-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4323573-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-04-06 | — | — | US | disclosed |
| US-4294831-A | ANTIVIRAL ACTIVITY | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4199574-A | Methods and compositions for treating viral infections and guanine acyclic nucleosides | BURROUGHS WELLCOME CO. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4146715-A | ANTIVIRAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-03-27 | — | — | US | disclosed |