Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.66 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.62 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PNP | P00491 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | EDNRA | P25101 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | HBB | P68871 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PI4KA | P42356 | 1/20 | 0.56 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.56 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.56 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.56 |
| ▸ | AHCY | P23526 | 7/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247503 | 0.87 | ENPP1 (0.60) | ADORA2AADORA1ENPP1NT5EPI4KA | |
| SCHEMBL10566016 | 0.85 | ENPP1 (0.59) | ADORA2AADORA1ENPP1NT5EPI4KA | |
| SCHEMBL20096689 | 0.85 | ADORA2A (0.66) | ADORA2AADORA1ENPP1NT5EPI4KA | |
| SCHEMBL25306268 | 0.84 | ENPP1 (0.61) | ADORA2AADORA1ENPP1NT5EPI4KA | |
| SCHEMBL8446150 | 0.84 | PNP (0.51) | ADORA2AADORA1ENPP1NT5EUSP2 | |
| SCHEMBL18786971 | 0.83 | ADORA2A (0.57) | ADORA2AADORA1ENPP1NT5EPI4KA | |
| SCHEMBL29385353 | 0.83 | ADORA2A (0.57) | ADORA2AADORA1ENPP1NT5EPI4KA | |
| SCHEMBL8561474 | 0.82 | ENPP1 (0.73) | ADORA2AADORA1ENPP1NT5EPNP | |
| SCHEMBL10582562 | 0.82 | PNP (0.50) | ADORA2AADORA1ENPP1NT5EUSP2 | |
| SCHEMBL10563489 | 0.82 | FDPS (0.50) | ADORA2AADORA1ENPP1NT5EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | ALT SOLUTIONS, INC. | 2009-08-13 | — | — | US | claimed |
| EP-2001488-A2 | PREVENTION AND TREATMENT OF CANCER AND OTHER DISEASES | Alt Solutions, Inc. (US) | 2008-12-17 | — | — | EP | claimed |
| WO-2007106561-A2 | PREVENTION AND TREATMENT OF CANCER AND OTHER DISEASES | ALT SOLUTIONS, INC. (US) | 2007-09-20 | — | — | WO | claimed |
| US-20230330126-A1 | MODIFIED ADENOSINE NUCLEOSIDE FOR USE IN THE TREATMENT OF VIRAL INFECTIONS | IACHETTINI GIAMPIETRO (IT) | 2023-10-19 | — | — | US | disclosed |
| EP-4175646-A1 | MODIFIED ADENOSINE NUCLEOSIDE FOR USE IN THE TREATMENT OF VIRAL INFECTIONS | Iachettini, Giampietro (IT) | 2023-05-10 | — | — | EP | disclosed |
| CN-115803033-A | Modified adenosine nucleosides for the treatment of viral infections | 詹皮特罗·亚切蒂尼 | 2023-03-14 | — | — | CN | disclosed |
| US-20220220135-A1 | HIGHLY SELECTIVE AND POTENT NPP1 INHIBITORS BASED ON URIDINE-5'-P,-DITHIOPHOSPHATE ANALOGUES | BAR-ILAN UNIVERSITY (IL) | 2022-07-14 | — | — | US | disclosed |
| WO-2022003531-A1 | MODIFIED ADENOSINE NUCLEOSIDE FOR USE IN THE TREATMENT OF VIRAL INFECTIONS | IACHETTINI GIAMPIETRO (IT) | 2022-01-06 | — | — | WO | disclosed |
| US-9067964-B2 | Complex and method for enhancing nuclear delivery | OLIGOMER SCIENCES AB (SE) | 2015-06-30 | — | — | US | disclosed |
| US-20140163037-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | TRANA DISCOVERY, INC. (US) | 2014-06-12 | — | — | US | disclosed |
| US-20110306138-A1 | COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY | OLIGOMER SCIENCES AB (SE) | 2011-12-15 | — | — | US | disclosed |
| EP-0273169-A2 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-07-06 | — | — | EP | disclosed |
| EP-0272446-A1 | Novel antiviral agents | SRI INTERNATIONAL (US) | 1988-06-29 | — | — | EP | disclosed |
| WO-1984004748-A2 | NOVEL ANTIVIRAL AGENTS | — | 1984-12-06 | — | — | WO | disclosed |
| US-4360522-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-11-23 | — | — | US | disclosed |
| US-4323573-A | VIRICIDES | BURROUGHS WELLCOME CO. (US) | 1982-04-06 | — | — | US | disclosed |
| US-4294831-A | ANTIVIRAL ACTIVITY | BURROUGHS WELLCOME CO. (US) | 1981-10-13 | — | — | US | disclosed |
| US-4287188-A | PARTICULARLY 9-(2-HYDROXYETHOXYMETHYL) GUANINE MONOPHOSPHATE AND SALTS, USEFUL AS ANTIVIRIAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1981-09-01 | — | — | US | disclosed |
| US-4199574-A | Methods and compositions for treating viral infections and guanine acyclic nucleosides | BURROUGHS WELLCOME CO. (US) | 1980-04-22 | — | — | US | disclosed |
| US-4146715-A | ANTIVIRAL AGENTS | BURROUGHS WELLCOME CO. (US) | 1979-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220135-A1 | HIGHLY SELECTIVE AND POTENT NPP1 INHIBITORS BASED ON URIDINE-5'-P,-DITHIOPHOSPHATE ANALOGUES | UPP1, NUDT14, UMPS | ADORA2A 2823/4885ADORA1 3253/4885ENPP1 24/4885 |
| US-20140163037-A1 | SCREENING METHODS FOR IDENTIFYING SPECIFIC STAPHYLOCOCCUS AUREUS INHIBITORS | NSUN3, RNGTT, TRMT1 | ADORA2A 2032/4885ADORA1 2579/4885ENPP1 3982/4885 |
| US-20090203636-A1 | Prevention and Treatment of Cancer and Other Diseases | TERT, POLRMT, RNASE1 | ADORA2A 1461/4885ADORA1 2194/4885ENPP1 214/4885 |
| US-20110306138-A1 | COMPLEX AND METHOD FOR ENHANCING NUCLEAR DELIVERY | SNRPE, SNRPA, HNRNPH3 | ADORA2A 1572/4885ADORA1 2916/4885ENPP1 2604/4885 |
| US-20230330126-A1 | MODIFIED ADENOSINE NUCLEOSIDE FOR USE IN THE TREATMENT OF VIRAL INFECTIONS | ADORA2A, ADORA3, ADORA2B | ADORA2A 1/4885ADORA1 5/4885ENPP1 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.