Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.57 |
| ▸ | PI4KA | P42356 | 2/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.57 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.57 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.57 |
| ▸ | NT5E | P21589 | 1/20 | 0.56 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | NSD3 | Q9BZ95 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | AHCY | P23526 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18786971 | 1.00 | ADORA2A (0.57) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL20096689 | 0.86 | ADORA2A (0.66) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL11247503 | 0.84 | ENPP1 (0.60) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL29878068 | 0.83 | ENPP1 (0.40) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL126904 | 0.83 | ENPP1 (0.40) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL357273 | 0.83 | FDPS (0.45) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL20404701 | 0.83 | ENPP1 (0.43) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL355371 | 0.83 | ENPP1 (0.40) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL31340868 | 0.83 | FDPS (0.45) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL2293269 | 0.83 | ADORA2A (0.66) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490505-A | MNK inhibitors | 和博医药有限公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-4200296-A1 | MNK INHIBITORS | Hepagene Therapeutics (HK) Limited (HK) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022038563-A1 | MNK INHIBITORS | Hepagene Therapeutics (HK) Limited (CN) | 2022-02-24 | — | — | WO | disclosed |
| CN-114026093-A | Compositions for treating neurodegenerative and mitochondrial diseases and methods of use thereof | 麦托吉宁公司 | 2022-02-08 | — | — | CN | disclosed |