Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 13/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244777 | 0.91 | MAPK14 (0.38) | TRPA1PTGESJAK2CSNK1DCSNK1E | |
| SCHEMBL11257687 | 0.90 | TRPA1 (0.35) | TRPA1PTGESPTPN1JAK2CSNK1D | |
| SCHEMBL11247663 | 0.86 | PTGES (0.40) | TRPA1PTGESJAK2CSNK1DCSNK1E | |
| SCHEMBL11258538 | 0.84 | PTGES (0.50) | PTGESJAK2 | |
| SCHEMBL3795732 | 0.82 | TRPA1 (0.39) | TRPA1PTGESPTPN1JAK2 | |
| SCHEMBL11249150 | 0.81 | PTGES (0.33) | TRPA1PTGESJAK2CSNK1DCSNK1E | |
| SCHEMBL11253397 | 0.80 | POLB (0.37) | TRPA1PTGESCSNK1DCSNK1EMAPK14 | |
| SCHEMBL11252253 | 0.78 | NR1H2 (0.34) | PTGESMAPK14 | |
| SCHEMBL11260762 | 0.78 | DHODH (0.38) | PTGES | |
| SCHEMBL11246023 | 0.75 | PDK2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |