Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 19/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244777 | 0.89 | MAPK14 (0.38) | PTGESJAK2PIM1CSNK2A2CSNK2B | |
| SCHEMBL11247663 | 0.85 | PTGES (0.40) | PTGESJAK2PIM1CSNK2A2CSNK2B | |
| SCHEMBL11247552 | 0.84 | TRPA1 (0.43) | PTGESJAK2 | |
| SCHEMBL13076580 | 0.81 | PTGES (0.51) | PTGESJAK2PIM1CSNK2A2CSNK2B | |
| SCHEMBL11251809 | 0.81 | PTGES (0.34) | PTGESJAK2PIM1CSNK2A2CSNK2B | |
| SCHEMBL11257687 | 0.80 | TRPA1 (0.35) | PTGESJAK2 | |
| SCHEMBL11249150 | 0.80 | PTGES (0.33) | PTGESJAK2 | |
| SCHEMBL11261743 | 0.79 | PTGES (0.36) | PTGESJAK2PIM1CSNK2A2CSNK2B | |
| SCHEMBL11252326 | 0.79 | PTGES (0.34) | PTGESJAK2PIM1CSNK2A2CSNK2B | |
| SCHEMBL11253397 | 0.79 | POLB (0.37) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314844-A | FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1982-02-09 | — | — | US | disclosed |