Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 9/20 | 0.70 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247632 | 1.00 | GPR34 (0.70) | GPR34PSMB5PTPN2PTPN1CDC25B | |
| SCHEMBL10727176 | 0.92 | GPR34 (0.73) | GPR34PSMB5GPR132KMT2AMEN1 | |
| SCHEMBL7970010 | 0.92 | GPR34 (0.73) | GPR34PSMB5GPR132KMT2AMEN1 | |
| SCHEMBL7296506 | 0.92 | GPR34 (0.73) | GPR34PSMB5GPR132KMT2AMEN1 | |
| SCHEMBL14588649 | 0.89 | NAALAD2 (0.59) | GPR34MMEACE | |
| SCHEMBL313387 | 0.84 | GPR34 (0.60) | GPR34MMEGPR132ACE | |
| SCHEMBL10726964 | 0.84 | ALDH1A1 (0.61) | GPR34KMT2AMEN1ALDH1A1 | |
| SCHEMBL4162326 | 0.83 | MME (0.63) | GPR34MMEITGB3ITGA2BACE | |
| SCHEMBL4160727 | 0.83 | MME (0.63) | GPR34MMEITGB3ITGA2BACE | |
| SCHEMBL4160723 | 0.83 | MME (0.63) | GPR34MMEITGB3ITGA2BACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001841-B1 | TYLOSIN DERIVATIVES | SANRAKU-OCEAN CO., LTD. (JP) | 1982-12-01 | — | — | EP | claimed |