SCHEMBL313387

SCHEMBL313387

O=C(COCc1ccccc1)NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR34 Q9UPC5 8/20 0.60
MME P08473 1/20 0.57
ACE P12821 3/20 0.54
FOLH1 Q04609 1/20 0.51
NAALAD2 Q9Y3Q0 1/20 0.51
GPR132 Q9UNW8 1/20 0.51
NOS2 P35228 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9417473 0.94 GPR34 (0.62) GPR34MMEACEGPR132NOS2
SCHEMBL2619549 0.88 MDM4 (0.65)
SCHEMBL2619554 0.86 GPR34 (0.70) GPR34MMEACEGPR132
SCHEMBL313074 0.84 MDM4 (0.55) GPR34ACE
SCHEMBL11247632 0.84 GPR34 (0.70) GPR34MMEACEGPR132
SCHEMBL11247627 0.84 GPR34 (0.70) GPR34MMEACEGPR132
SCHEMBL4160727 0.83 MME (0.63) GPR34MMEACEFOLH1NAALAD2
SCHEMBL4162323 0.83 MME (0.63) GPR34MMEACEFOLH1NAALAD2
SCHEMBL4162326 0.83 MME (0.63) GPR34MMEACEFOLH1NAALAD2
SCHEMBL4160723 0.83 MME (0.63) GPR34MMEACEFOLH1NAALAD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
US-8664426-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2014-03-04 US disclosed
EP-1948713-B1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2013-12-04 EP disclosed
US-20130317118-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-11-28 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-8519175-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2013-08-27 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2013-01-31 US disclosed
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2012-04-19 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-8093420-B2 Functionalized amino acids and absorbable polymers therefrom BEZWADA BIOMEDICAL, LLC (US) 2012-01-10 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL, LLC (US) 2009-04-16 US disclosed
EP-1948713-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM Bezwada Biomedical LLC (US) 2008-07-30 EP disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 WO disclosed
WO-2007047244-A2 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BEZWADA BIOMEDICAL LLC (US) 2007-04-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098180-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 GPR34 1564/4885MME 1226/4885ACE 940/4885
US-20120094994-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 GPR34 1564/4885MME 1226/4885ACE 940/4885
US-20130030061-A1 FUNCTIONALIZED AMINO ACIDS AND ABSORBABLE POLYMERS THEREFROM BCAT2, BCAT1, SLC7A1 GPR34 1564/4885MME 1226/4885ACE 940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.