Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | IAPP | P10997 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11170458 | 0.84 | KDM5A (0.58) | KDM5AADRB2MAPK1ADRB1ADRB3 | |
| SCHEMBL6812666 | 0.81 | KDM5A (0.50) | KDM5AADRB2MAPK1ALOX15ADRB1 | |
| SCHEMBL7259369 | 0.81 | ADRA2A (0.55) | KDM5AADRB2MAPK1ALOX15ADRB1 | |
| SCHEMBL4513447 | 0.79 | KDM4E (0.54) | FFAR1MAPK1ALOX15KEAP1IAPP | |
| SCHEMBL6475595 | 0.78 | KDM5A (0.47) | KDM5AADRB2MAPK1ADRB1ADRB3 | |
| SCHEMBL13074401 | 0.77 | KDM5A (0.53) | KDM5AADRB2MAPK1ALOX15ADRB1 | |
| SCHEMBL4515340 | 0.76 | HDAC1 (0.60) | MAPK1ALOX15 | |
| Hydrochloric Acid SCHEMBL11670336 | 0.76 | ADRB2 (0.55) | KDM5AADRB2ADRB1ADRB3SLC6A4 | |
| Dihydrocaffeic Acid SCHEMBL7058919 | 0.76 | IAPP (0.65) | FFAR1ADRB2MAPK1ALOX15KEAP1 | |
| Dihydrocaffeic Acid SCHEMBL245530 | 0.76 | IAPP (0.65) | FFAR1ADRB2MAPK1ALOX15KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062440-A1 | Process for preparing phenylalkanoic acids and derivatives of benzoxazole therefrom | ELI LILLY AND COMPANY (US) | 1982-10-13 | — | — | EP | claimed |
| EP-0062440-A1 | Process for preparing phenylalkanoic acids and derivatives of benzoxazole therefrom | ELI LILLY AND COMPANY (US) | 1982-10-13 | — | — | EP | disclosed |