SCHEMBL11247871

SCHEMBL11247871

CC(=O)NOS(=O)(=O)ONC(C)=O

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.35
KDM4E B2RXH2 1/20 0.35
PTGS1 P23219 1/20 0.35
MMP12 P39900 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CRBN Q96SW2 1/20 0.35
NFKB1 P19838 1/20 0.33
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
TAS2R38 P59533 1/20 0.32
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
BLM P54132 1/20 0.32
PMP22 Q01453 1/20 0.32
DHFR P00374 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
CA12 O43570 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28826281 0.80
SCHEMBL28243453 0.80
SCHEMBL28244356 0.77 F2 (0.36) CA2ALDH1A1CA1CA9TSHR
Potassium Ion SCHEMBL29107399 0.76 CA2 (0.32) CA2KDM4EPTGS1MMP12ALDH1A1
SCHEMBL28693479 0.76 CRBN (0.31) CA2KDM4EPTGS1MMP12ALDH1A1
SCHEMBL11281646 0.76
SCHEMBL27832944 0.74 ALDH1A1 (0.39) KDM4EALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL27895540 0.74 DHFR (0.35) DHFRTSHRSMN1; SMN2TDP1
SCHEMBL2511148 0.73 TSHR (0.37) CA2CRBNNFKB1CA9LMNA
SCHEMBL28954310 0.72 F2 (0.36) CA2ALDH1A1CA1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106188341-B Heparin sodium leftover bits and pieces prepares high-purity sulfuric acid dermatan technique 河北常山生化药业股份有限公司 2019-09-17 CN disclosed
CN-108530561-A A method of it is produced from heparin and extracts high-purity sulphuric acid heparan in waste 深圳市格利科生物科技有限公司 2018-09-14 CN disclosed
US-4361516-A N-Monosubstituted indoanilines SOCIETE ANONYME DITE: L'OREAL (FR) 1982-11-30 US disclosed