Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244801 | 0.75 | LMNA (0.42) | OPRM1 | |
| SCHEMBL11256394 | 0.73 | LMNA (0.42) | — | |
| SCHEMBL28739222 | 0.73 | SLC22A1 (0.62) | HTR2AHTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL11244360 | 0.72 | LMNA (0.41) | SLC6A4SLC6A2 | |
| SCHEMBL11252284 | 0.70 | LMNA (0.39) | SLC6A4SLC6A2 | |
| SCHEMBL28739214 | 0.69 | SLC22A1 (0.68) | HTR2AHTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL11079566 | 0.69 | MEN1 (0.33) | SLC6A4SLC6A2OPRM1SLC6A3 | |
| SCHEMBL14579047 | 0.65 | CHRM2 (0.63) | HTR2AHTR2CHTR2BSLC6A4SLC6A2 | |
| SCHEMBL11591002 | 0.65 | HTR2C (0.62) | HTR2AHTR2CHTR2BSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL17420822 | 0.64 | CHRM2 (0.61) | HTR2AHTR2CHTR2BSLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337341-A | 4a-Aryl-octahydro-1H-2-pyrindines | ELI LILLY AND COMPANY (US) | 1982-06-29 | — | — | US | disclosed |