Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244360 | 0.85 | LMNA (0.41) | LMNAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11256394 | 0.85 | LMNA (0.42) | LMNAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11252284 | 0.83 | LMNA (0.39) | LMNAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11247876 | 0.75 | HTR2A (0.43) | OPRM1 | |
| SCHEMBL11248709 | 0.67 | HSD11B1 (0.45) | LMNAKMT2AOPRM1OPRL1HTT | |
| Benzoic Acid SCHEMBL10818979 | 0.67 | MEN1 (0.36) | LMNAALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11079566 | 0.66 | MEN1 (0.33) | ALDH1A1MEN1KMT2APOLBOPRM1 | |
| SCHEMBL14980950 | 0.66 | ALDH1A1 (0.39) | LMNAALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11250668 | 0.63 | GAA (0.44) | ALDH1A1MEN1KMT2AOPRM1OPRL1 | |
| SCHEMBL11547438 | 0.63 | TSHR (0.39) | LMNAALDH1A1MEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337341-A | 4a-Aryl-octahydro-1H-2-pyrindines | ELI LILLY AND COMPANY (US) | 1982-06-29 | — | — | US | disclosed |