Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.41 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25052896 | 0.84 | TP53 (0.55) | ALOX15TP53HPGDLMNACYP3A4 | |
| SCHEMBL29433129 | 0.84 | ALOX15 (0.80) | ALOX15TP53HPGDLMNACYP3A4 | |
| SCHEMBL158789 | 0.84 | ALOX15 (0.80) | ALOX15TP53HPGDLMNACYP3A4 | |
| SCHEMBL5082769 | 0.82 | ALOX15 (0.84) | ALOX15TP53HPGDLMNACYP3A4 | |
| SCHEMBL12401755 | 0.82 | LMNA (0.53) | ALOX15TP53HPGDLMNACYP3A4 | |
| SCHEMBL11003488 | 0.79 | HTT (0.48) | HPGDDPP4HSD17B10TSHRHTT | |
| SCHEMBL12388590 | 0.78 | LMNA (0.50) | ALOX15TP53HPGDLMNACYP3A4 | |
| SCHEMBL15044110 | 0.78 | ALOX15 (0.66) | ALOX15TP53HPGDLMNACYP3A4 | |
| SCHEMBL14285750 | 0.78 | LMNA (0.59) | ALOX15TP53HPGDLMNACYP3A4 | |
| SCHEMBL39215 | 0.78 | ALOX15 (1.00) | ALOX15TP53HPGDLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4312887-A | 2-Hydroxylaminomethyl phenols | ABBOTT LABORATORIES (US) | 1982-01-26 | — | — | US | disclosed |
| US-4029816-A | ANTIHYPERTENSIVE, DIURETIC, SALURETIC | MERCK & CO., INC. (US) | 1977-06-14 | — | — | US | disclosed |