Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.84 |
| ▸ | TP53 | P04637 | 3/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.84 |
| ▸ | LMNA | P02545 | 2/20 | 0.84 |
| ▸ | HPGD | P15428 | 1/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.58 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL39215 | 0.91 | ALOX15 (1.00) | ALOX15TP53CYP3A4LMNAHPGD | |
| SCHEMBL29381356 | 0.91 | ALOX15 (1.00) | ALOX15TP53CYP3A4LMNAHPGD | |
| SCHEMBL158789 | 0.89 | ALOX15 (0.80) | ALOX15TP53CYP3A4LMNAHPGD | |
| SCHEMBL29433129 | 0.89 | ALOX15 (0.80) | ALOX15TP53CYP3A4LMNAHPGD | |
| SCHEMBL2789595 | 0.89 | ALOX15 (0.80) | ALOX15TP53CYP3A4LMNAHPGD | |
| SCHEMBL18198041 | 0.84 | ALOX15 (0.79) | ALOX15TP53CYP3A4LMNAHPGD | |
| SCHEMBL92809 | 0.84 | CYP3A4 (0.64) | ALOX15TP53CYP3A4LMNAHPGD | |
| SCHEMBL15044110 | 0.83 | ALOX15 (0.66) | ALOX15TP53CYP3A4LMNAHPGD | |
| SCHEMBL11247895 | 0.82 | ALOX15 (0.63) | ALOX15TP53CYP3A4LMNAHPGD | |
| SCHEMBL13939800 | 0.81 | ALOX15 (0.68) | ALOX15TP53CYP3A4LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | GUANGDONG OXO CHEM LTD. (CN) | 2025-01-14 | — | — | US | claimed |
| CN-115385960-A | Preparation method and application of oxaspiro compound with large steric hindrance | 惠州凯特立斯科技有限公司 | 2022-11-25 | — | — | CN | claimed |
| US-20220242891-A1 | SPIRO-BISPHOSPHOROUS COMPOUND, AND PREPARATION AND APPLICATION THEREOF | GUANGDONG OXO CHEM LTD. (CN) | 2022-08-04 | — | — | US | claimed |
| US-11306112-B2 | Biphenyl tetradentate phosphite compound: preparation method and application thereof | GUANGDONG OXO CHEM LTD. (CN) | 2022-04-19 | — | — | US | claimed |
| CN-112159313-A | Preparation method of big steric-hindrance bi-phenol skeleton and phosphonite ligand thereof | 惠州凯特立斯科技有限公司 | 2021-01-01 | — | — | CN | claimed |
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | GUANGDONG OXO CHEM LTD. (CN) | 2025-01-14 | — | — | US | disclosed |
| CN-112159313-B | Preparation method of large-steric-hindrance biphenol skeleton and phosphonite ligand thereof | 广东欧凯新材料有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-115385960-A | Preparation method and application of oxaspiro compound with large steric hindrance | 惠州凯特立斯科技有限公司 | 2022-11-25 | — | — | CN | disclosed |
| US-20220242891-A1 | SPIRO-BISPHOSPHOROUS COMPOUND, AND PREPARATION AND APPLICATION THEREOF | GUANGDONG OXO CHEM LTD. (CN) | 2022-08-04 | — | — | US | disclosed |
| US-11306112-B2 | Biphenyl tetradentate phosphite compound: preparation method and application thereof | GUANGDONG OXO CHEM LTD. (CN) | 2022-04-19 | — | — | US | disclosed |
| CN-112159313-A | Preparation method of big steric-hindrance bi-phenol skeleton and phosphonite ligand thereof | 惠州凯特立斯科技有限公司 | 2021-01-01 | — | — | CN | disclosed |
| US-20080125531-A1 | Polymerizable Composition, Thermoplastic Resin Composition, Crosslinked Resin, And Crosslinked Resin Composite Materials | ZEON COROPRATION (JP) | 2008-05-29 | — | — | US | disclosed |
| CN-100365039-C | Polymerizable composition, thermoplastic resin composition, crosslinked resin, and crosslinked resin composite materials | ZEON CORP (JP) | 2008-01-30 | — | — | CN | disclosed |
| CN-1764681-A | Polymerizable composition, thermoplastic resin composition, crosslinked resin, and crosslinked resin composite materials | ZEON CORP (JP) | 2006-04-26 | — | — | CN | disclosed |
| EP-1589054-A1 | POLYMERIZABLE COMPOSITION, THERMOPLASTIC RESIN COMPOSITION, CROSSLINKED RESIN, AND CROSSLINKED RESIN COMPOSITE MATERIALS | Zeon Corporation (JP) | 2005-10-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12195489-B2 | Spiro-bisphosphorous compound, and preparation and application thereof | SOST, BPGM, PFKFB3 | ALOX15 1580/4885TP53 4326/4885CYP3A4 1587/4885 |
| US-20220242891-A1 | SPIRO-BISPHOSPHOROUS COMPOUND, AND PREPARATION AND APPLICATION THEREOF | SOST, BPGM, PFKFB3 | ALOX15 1580/4885TP53 4326/4885CYP3A4 1587/4885 |
| US-11306112-B2 | Biphenyl tetradentate phosphite compound: preparation method and application thereof | TYMP, NUDT1, PHOSPHO1 | ALOX15 2242/4885TP53 808/4885CYP3A4 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.