Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256491 | 0.84 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL11257421 | 0.82 | APEX1 (0.45) | ALDH1A1SLC6A4FSCN1APEX1 | |
| Hydrochloric Acid SCHEMBL11639231 | 0.81 | APEX1 (0.44) | ALDH1A1SLC6A4FSCN1APEX1 | |
| SCHEMBL11250322 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL11268173 | 0.78 | MEN1 (0.41) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| Hydrochloric Acid SCHEMBL11724538 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTHTT | |
| SCHEMBL11253602 | 0.76 | ALDH1A1 (0.40) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL11268824 | 0.75 | KDR (0.44) | — | |
| Hydrochloric Acid SCHEMBL11727190 | 0.74 | KDR (0.43) | — | |
| SCHEMBL9638977 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTHPGDHTTFSCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358611-A | FROM A PHENYLHYDRAZINE, A CHLOROFORMATE, PHOSGENE AND A SECONDARY AMINE | SHELL OIL COMPANY (US) | 1982-11-09 | — | — | US | disclosed |