Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253466 | 0.84 | RORC (0.48) | ALDH1A1MAPK1SMN1; SMN2HPGDMEN1 | |
| SCHEMBL11257421 | 0.82 | APEX1 (0.45) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11639231 | 0.81 | APEX1 (0.44) | ALDH1A1 | |
| SCHEMBL11674121 | 0.79 | LMNA (0.43) | ALDH1A1MAPK1SMN1; SMN2TP53NPSR1 | |
| SCHEMBL11252696 | 0.78 | GPBAR1 (0.38) | ALDH1A1SMN1; SMN2HPGDNPSR1MEN1 | |
| SCHEMBL11268173 | 0.78 | MEN1 (0.41) | ALDH1A1SMN1; SMN2PKMHPGDMEN1 | |
| SCHEMBL11250322 | 0.78 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL11724538 | 0.77 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| Hydrochloric Acid SCHEMBL11691897 | 0.76 | SMN1; SMN2 (0.39) | ALDH1A1MAPK1SMN1; SMN2TP53PKM | |
| SCHEMBL11248074 | 0.76 | ALDH1A1 (0.36) | ALDH1A1HPGDMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358611-A | FROM A PHENYLHYDRAZINE, A CHLOROFORMATE, PHOSGENE AND A SECONDARY AMINE | SHELL OIL COMPANY (US) | 1982-11-09 | — | — | US | disclosed |