Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011833 | 0.79 | TAAR1 (0.59) | SIGMAR1LTA4HTAAR1 | |
| SCHEMBL11252300 | 0.79 | OPRM1 (0.51) | — | |
| SCHEMBL19681498 | 0.78 | MAOB (0.60) | HTTHRH3 | |
| SCHEMBL11247858 | 0.77 | TDP1 (0.45) | HRH3MAPTHPGDLTA4H | |
| SCHEMBL3367622 | 0.74 | LTA4H (0.48) | HTTSIGMAR1LTA4H | |
| SCHEMBL11157781 | 0.72 | TAAR1 (0.59) | HRH3SIGMAR1LTA4HTAAR1 | |
| SCHEMBL3365060 | 0.71 | LTA4H (0.51) | HTTHRH3LTA4H | |
| SCHEMBL16838790 | 0.71 | MAOB (0.63) | HRH3SIGMAR1TAAR1 | |
| SCHEMBL19072185 | 0.70 | TAAR1 (0.57) | SIGMAR1LTA4HTAAR1 | |
| SCHEMBL11239119 | 0.70 | MMP8 (0.47) | HTTHRH3HPGDTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311708-A | ADRENERGIC BLOCKING AGENTS | SYNTHELABO (FR) | 1982-01-19 | — | — | US | disclosed |
| US-4252984-A | 1-/P-/2-/CYCLOPROPYLMETHOXY/ETHYL/PHENOXY/-3-ISOPROPYLAMINO-2 -PROPANOL | SYNTHELABO (FR) | 1981-02-24 | — | — | US | disclosed |